Bad Eyes(-1): Your eyes have started to seriously degrade from the radiation in the world, your genetics aren't helping much either, and you will be blind by the time you're middle-aged. -1 to all Percep-related rolls.
Ugly(-1): NPCs have an automatically slight aversion to you, for your physical deformity and the deformities to your stance, gait, and speech.
Toxin Susceptible(-1): You are very susceptible to toxins. If you are poisoned, you take double effect from the toxin, the toxin lasts twice as long, or it takes half the amount of time for the final effect of the toxin to take place. If more than one of these applies, you take double effect from the toxin. This also applies to the effects of drugs.
Night Blindness(-1): Your eyes don't do well in very dim lighting. -1 to all rolls in dark conditions. Cannot be taken with Night Vision.
Daylight Blindness(-1): Sunlight and bright lights hurt your eyes. -1 to all rolls in these conditions. Cannot be negated by eyewear.
Slow(-1): Your movements are slow and ponderous. -1 to all agility rolls.
Sensitive ears(-1): When there are loud noises, like alarms, gunfire, or anything else the GM determines to be a 'loud noise', you take a -1 to all rolls.
Frail(-1): You were a C-student in gym class. -1 to all Str rolls.
Dumb(-1): When you were a kid, everyone recommended you learn the phrase, "You want fries with your brahmin burger?". Unfortunately, you didn't get it. -1 to all Int and Tech rolls.
Sick(-2): That anemia and bronchitis will catch up with you eventually, chummer. -5 HP per level.
Deaf and Blind(-2): Your eyes are dim, your ears ringing all the time. -4 to all Percep rolls.
Crippled(-2): Your muscles are atrophied and non-responsive. -4 to all Str rolls.
Dumb As A Brick(-2): Your mind simply can't grasp more complicated processes. -3 to all Int and Tech rolls.
Stiff:(-2): Your muscles are unresponsive, your joints stiff and tight. -4 to all agility rolls.
Osteogenesis imperfecta(-3): Your bones are brittle and crack easily. +5 damage per hit against you.
Combat Monster(-3) : Your body chemistry pumps far too much androgen, testosterone, and adrenaline into your system, and you just can't seem to control your temper. What does that mean? You're a combat monster. When given the chance for combat (tense situations, threats), you must make an Int/Level/Luck roll. If you fail, you must immediately attack a hostile, or "hostile", opponent. Additionally, you must make an Int/Level/Luck roll to stop fighting, or else you start attacking "friendlies". You can make another Int/Level/Luck roll every round to try to exit the frenzy.
Passive(-3): Your mind has been scarred by the horrors of the wasteland and the city to the point that your mind siezes up during a fight or flight situation. You need to make an Int/Level/Luck roll to actually start or join combat, and every 2 rounds, you must make another one or else stop fighting. You can retry 2 rounds later if you fail.